Tyroserleutide hydrochloride
CAS No. 852982-42-4
Tyroserleutide hydrochloride ( —— )
产品货号. M30297 CAS No. 852982-42-4
Tyroserleutide hydrochloride is a small molecule tripeptide isolated from the degradation product of pig spleen, which can inhibit tumor growth in vivo and in vitro.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1361 | 有现货 |
|
10MG | ¥2362 | 有现货 |
|
25MG | ¥4471 | 有现货 |
|
50MG | ¥6869 | 有现货 |
|
100MG | ¥11534 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
5MG | ¥1361 | 有现货 |
|
10MG | ¥2362 | 有现货 |
|
25MG | ¥4471 | 有现货 |
|
50MG | ¥6869 | 有现货 |
|
100MG | ¥11534 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Tyroserleutide hydrochloride
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Tyroserleutide hydrochloride is a small molecule tripeptide isolated from the degradation product of pig spleen, which can inhibit tumor growth in vivo and in vitro.
-
产品描述Tyroserleutide hydrochloride is a small molecule tripeptide isolated from the degradation product of pig spleen, which can inhibit tumor growth in vivo and in vitro.(In Vitro):Tyroserleutide (YSL) exhibits immuno-modulating effects, such as enhancing concanavalin (ConA) induced proliferation of mouse spleen lymphocytes, phagocytosis of mouse peritoneal macrophages, and the activity of natural killer (NK) cells. Tyroserleutide (YSL), an immunologically therapeutic tripeptide, can promote hepatocarcinoma cell (H22) apoptosis through downregulating Bcl-2 and cyclin D1 expression. Tyroserleutide is an ideal choice for inducing apoptosis of liver tumor cells. Tyroserleutide inhibits tumor growth and does not cause severe toxicities in the major organs. Tyroserleutide can inhibit tumor cell migration.(In Vivo):Tyroserleutide (10-80 μg/kg; injection (i.p.) one time every day until mice are dead) displays obvious anti-tumor activity. Tyroserleutide significantly prolongs the survival time of the murine H22 implanted mice.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Antitumor tripeptide
-
研究领域——
-
适应症——
化学信息
-
CAS Number852982-42-4
-
分子量417.9
-
分子式C18H28ClN3O6
-
纯度>98% (HPLC)
-
溶解度DMSO : 250 mg/mL (598.26 mM; Need ultrasonic)
-
SMILES——
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
Wang C, et al. Studies on the large scale synthesis and anti-tumor activity of YSL. Prep Biochem Biotechnol. 2003 Aug;33(3):189-95.
产品手册
关联产品
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
Lubiprostone
Lubiprostone is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.